Each of my pet portraits takes hours to complete. I don't use quick Photoshop filters. My paintings are the result of thousands of strokes 'by hand' - a relaxing and satisfying process.
There are no fumes and no mess. No paint on clothes or the carpet. No waiting for paint to dry - oil paint can take a week or more between layers. There's more freedom to be creative and try out ideas (without resulting in a ruined painting and wasted expensive materials).
I painted Marbles from a photo I took during a pet sitting visit. I used a stylus as a brush to stroke a small graphics tablet (canvas). I can curl up on the couch with the tablet on my lap. I usually paint in when everyone has gone to bed and there are no distractions. I saved the painting at various stages to illustrate how a painting progresses.
I use ArtRage, a reasonably priced, easy to use art program that is reportedly less buggy than Corel Painter. Digital painting uses lots of computer memory and files can be very large with all their layers, especially if saved at a high resolution required for printing. My computer copes well with a high resolution painting file to print at 10 x 8 inches on photo paper. I haven't tried larger sizes yet.